A H2S donor
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Sodium Hydrogen Sulfide (hydrate)

Item No. 10012555

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
sodium sulfide, hydrate
CAS Number
207683-19-0
Synonyms
  • NaHS
  • NSC 158264
  • Sodium Hydrosulfide
Molecular Formula
HNaS • XH2O
Formula Weight
56.1
Purity
≥65%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 3 mg/mlDMSO: 3 mg/mlEthanol: 3 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
224 nm
SMILES
[Na]S.O
InChi Code
InChI=1S/Na.H2O.H2S/h;2*1H2/q+1;;/p-1
InChi Key
ZNKXTIAQRUWLRL-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 g

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    Cayman Chemical
    Neutrophil Biology Wall Poster

    Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.

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    Product Description

    Hydrogen sulfide (H2S) is, like nitric oxide, an important gaseous mediator that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. Sodium hydrogen sulfide is an H2S donor commonly used in cellular and whole animal experimental systems. For example, it has been used to suggest that H2S promotes neutrophil migration, reduces airway inflammation, and protects neurites, heart, and intestine1 from chemical or ischemic-reperfusion damage.2,3,4,5,1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Liu, H., Bai, X.B., Shi, S., et al. Hydrogen sulfide protects from intestinal ischaemia-reperfusion injury in rats. J. Pharm. Pharmacol. 61(2), 207-212 (2009).

    2. Dal-Secco, D., Cunha, T.M., Freitas, A., et al. Hydrogen sulfide augments neutrophil migration through enhancement of adhesion molecule expression and prevention of CXCR2 internalization: Role of ATP-sensitive potassium channels. J. Immunol. 181(6), 4287-4298 (2008).

    3. Chen, Y.H., Wu, R., Geng, B., et al. Endogenous hydrogen sulfide reduces airway inflammation and remodeling in a rat model of asthma. Cytokine 45(2), 117-123 (2009).

    4. Hu, L.F., Lu, M., Wu, Z.Y., et al. Hydrogen sulfide inhibits rotenone-induced apoptosis via preservation of mitochondrial function. Mol. Pharmacol. 75(1), 27-34 (2009).

    5. Yong, Q.C., Lee, S.W., Foo, C.S., et al. Endogenous hydrogen sulphide mediates the cardioprotection induced by ischemic postconditioning. Am. J. Physiol. Heart Circ. Physiol. 295(3), H1330-H1340 (2008).