A derivative of PGF2α 2-glyceryl ester
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Prostaglandin F2α serinol amide

Item No. 10194

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[(2-hydroxy-1-hydroxymethyl)ethyl]-9α,11α,15S-trihydroxy-prosta-5Z,13E-dien-1-amide
CAS Number
1135226-99-1
Synonyms
  • PGF2α-SA
  • PTD18
Molecular Formula
C23H41NO6
Formula Weight
427.6
Purity
≥98%
Formulation (Request formulation change)
A 10 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 25 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 5 mg/ml
SMILES
O[C@@H]1[C@H](C/C=C\CCCC(N([H])C(CO)CO)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1
InChi Code
InChI=1S/C23H41NO6/c1-2-3-6-9-18(27)12-13-20-19(21(28)14-22(20)29)10-7-4-5-8-11-23(30)24-17(15-25)16-26/h4,7,12-13,17-22,25-29H,2-3,5-6,8-11,14-16H2,1H3,(H,24,30)/b7-4-,13-12+/t18-,19+,20+,21-,22+/m0/s1
InChi Key
IRAOUIWKWHBHDC-GKUWGJHRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    5 mg

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    10 mg

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    Product Description

    Prostaglandin F2α serinol amide (PGF2α-SA) is a derivative of the 2-arachidonyl glycerol (2-AG) metabolite PGF2α 2-glyceryl ester (PGF2α-G).1 It induces calcium mobilization in RAW 264.7 macrophages and H1819 cells (EC50s = 3.7 and 1.2 pM, respectively).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Richie-Jannetta, R., Nirodi, C.S., Crews, B.C., et al. Structural determinants for calcium mobilization by prostaglandin E2 and prostaglandin F2α glyceryl esters in RAW 264.7 cells and H1819 cells. Prostaglandins Other Lipid Mediat. 92(1-4), 19-24 (2010).