Active, pure human recombinant enzyme
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

PRMT1 (human, recombinant)

Item No. 10350

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • Interferon receptor 1-bound protein 4
  • Protein Arginine Methyltransferase 1
Purity
≥80% estimated by SDS-PAGE
Source
Active recombinant N-terminal GST-tagged protein expressed in E. coli
Amino Acids
2-371 (full-length)
MW
69.2 kDa
Formulation (Request formulation change)
40 mM Tris-HCl, pH 8.0, 110 mM sodium chloride, 2.2 mM potassium chloride, 0.04% Tween-20, 20% glycerol, and 3 mM DTT
UniProt Accession №
Q99873
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    50 µg

    $363

    Add
    Product Description

    Protein Arginine Methyltransferases (PRMTs) are S-adenosyl-L-methionine-dependent enzymes that catalyze post-translational modification of arginine residues by methylation in three different ways: monomethylation, symmetric dimethylation, or asymmetric dimethylation at terminal arginine guanidino nitrogen atoms.1 Class I PRMTs catalyze arginine monomethylation and asymmetric dimethylation. PRMT1 is a class I arginine methyltransferase that methylates arginine residues at a number of glycine and arginine rich regions (GAR motifs) in proteins including histone H4 at arginine 3.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bedford, M.T. Arginine methylation at a glance. J. Cell Sci. 120(24), 4243-4246 (2007).

    2. Wang, H., Huang, Z.Q., Xia, L., et al. Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor. Science 293, 853-857 (2001).