Lipophilic prodrug form of PGE2
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Prostaglandin E2 isopropyl ester

Item No. 10384

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
11α,15S-dihydroxy-9-oxo-prosta-5Z,13E-dien-1-oic acid, 1-methylethyl ester
CAS Number
71845-66-4
Molecular Formula
C23H38O5
Formula Weight
394.5
Purity
≥98%
Formulation (Request formulation change)
A 10 mg/ml solution in methyl acetate
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 50 mg/mlEthanol: 50 mg/mlPBS (pH 7.2): <50 µg/ml
SMILES
O=C1[C@H](C/C=C\CCCC(OC(C)C)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1
InChi Code
InChI=1S/C23H38O5/c1-4-5-8-11-18(24)14-15-20-19(21(25)16-22(20)26)12-9-6-7-10-13-23(27)28-17(2)3/h6,9,14-15,17-20,22,24,26H,4-5,7-8,10-13,16H2,1-3H3/b9-6-,15-14+/t18-,19+,20+,22+/m0/s1
InChi Key
NOHLKSJQMSPOTB-FZNVCOGTSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

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    5 mg

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    10 mg

    $481

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    Product Description

    Prostaglandin E2 (PGE2) isopropyl ester is a more lipophilic form of the free acid, PGE2. PG esters have enhanced lipid solubility compared to their parent compounds. They are generally hydrolyzed to the free acid by endogenous esterases upon in vivo administration, making the esters useful prodrugs. In general, the C-1 esters of PGs show greatly diminished receptor activity in vitro compared to the parent free acids.

    WARNING This product is not for human or veterinary use.