An Analytical Reference Standard
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Unlabeled Version(s)
10266JWH 007
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JWH 007-d9

Item No. 10486

Restricted Product (Schedule I)
Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2-methyl-1-pentyl-1H-indol-3-yl)-1-naphthalenyl-2,2,3,3,4,4,5,5,5-d9-methanone
CAS Number
1651833-48-5
Molecular Formula
C25H16D9NO
Formula Weight
364.5
Purity
≥99% deuterated forms (d1-d9)
Formulation
A 1 mg/ml solution in methyl acetate
Solubility(Learn about Variance in Solubility)
DMF: 2.5 mg/mlDMSO: 1.5 mg/mlEthanol: 0.15 mg/ml
λmax
218, 319 nm
SMILES
O=C(C1=C(C)N(CC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])C2=C1C=CC=C2)C3=CC=CC4=C3C=CC=C4
InChi Code
InChI=1S/C25H25NO/c1-3-4-9-17-26-18(2)24(22-14-7-8-16-23(22)26)25(27)21-15-10-12-19-11-5-6-13-20(19)21/h5-8,10-16H,3-4,9,17H2,1-2H3/i1D3,3D2,4D2,9D2
InChi Key
IBBNKINXTRKICJ-ZYWCKPJZSA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    JWH 007-d9 (Item No. 10486) is intended for use as an internal standard for the quantification of JWH 007 (Item No. 10266) by GC- or LC-MS. JWH 007 is a potent cannabinoid (CB) receptor agonist that avidly binds to both CB1 and CB2 (Ki = 9.5 and 2.9 nM, respectively).1,2 This compares favorably with the binding of Δ9-THC, which binds CB1 and CB2 with Ki values of 41 and 36 nM, respectively.2 Similarly, JWH 007 performs comparably to Δ9-THC in murine studies on spontaneous activity, antinociception, hypothermia, and catalepsy.1 This product is intended for forensic and research purposes.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Huffman, J.W., Dai, D., Martin, B.R., et al. Design, synthesis and pharmacology of cannabimimetic indoles. Bioorg. Med. Chem. Lett. 4(4), 563-566 (1994).

    2. Huffman, J.W., Zengin, G., Wu, M.J., et al. Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB1 and CB2 receptors: Steric and electronic effects of naphthoyl substituents. New highly selective CB2 receptor agonists. Bioorg. Med. Chem. 13(1), 89-112 (2005).