A C32:6 very long chain fatty acid
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Product Categories

Product Type

Biochemicals
Lipids
Fatty Acids

Research Area

Lipid Biochemistry
Fatty Acids

CAY10632

Item No. 10497

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
14Z,17Z,20Z,23Z,26Z,29Z-dotriacontahexaenoic acid
CAS Number
105517-82-6
Synonyms
  • FA 32:6
Molecular Formula
C32H52O2
Formula Weight
468.8
Purity
≥98%
Formulation (Request formulation change)
A 5 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
0.15 M Tris-HCl pH 8.5: .5 mg/mlDMF: 50 mg/mlDMSO: 50 mg/mlEthanol: 50 mg/ml
SMILES
CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCCCCCCCCCC(O)=O
InChi Code
InChI=1S/C32H52O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23-24-25-26-27-28-29-30-31-32(33)34/h3-4,6-7,9-10,12-13,15-16,18-19H,2,5,8,11,14,17,20-31H2,1H3,(H,33,34)/b4-3-,7-6-,10-9-,13-12-,16-15-,19-18-
InChi Key
HIKGLCYKBLODNY-KUBAVDMBSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    500 µg

    $132

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    1 mg

    $227

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    Product Description

    Very long chain polyunsaturated fatty acids (VLCPUFA) are present in retina, sperm, and brain.1,2,3 Though little is known of their biosynthesis or functional roles in these tissues, recent studies using the elongation of very long-chain FA-4 protein suggest a unique role for VLCPUFA in retinal development and macular degeneration.4,5 CAY10632 is a C32:6 VLCPUFA whose specific biological actions are largely unknown, but are thought to involve normal photoreceptor cell function in the retina.4,6

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Aveldaño, M.I. Phospholipid species containing long and very long polyenoic fatty acids remain with rhodopsin after hexane extraction of photoreceptor membranes. Biochemistry 27(4), 1229-1239 (1988).

    2. Robinson, B.S., Johnson, D.W., and Poulos, A. Novel molecular species of spingomyelin containing 2-hydroxylated polyenoic very-long-chain fatty acids in mammalian testes and spermatozoa. The Journal of Biological Chemisty 267(3), 1746-1751 (1992).

    3. Robinson, B.S., Johnson, D.W., and Poulos, A. Unique molecular species of phophatidylcholine containing very-long-chain (C24-C38) polyenoic fatty acids in rat brain. Biochem. J. 265(3), 763-767 (1990).

    4. McMahon, A., Jackson, S.N., Woods, A.S., et al. A Stargardt disease-3 mutation in the mouse Elovl4 gene causes retinal deficiency of C32-C36 acyl phosphatidylcholines. FEBS Lett. 581(28), 5459-5463 (2007).

    5. Agbaga, M.P., Mandal, M.N.A., and Anderson, R.E. Retinal very long-chain PUFAs: New insights from studies on ELOVL4 protein. J. Lipid Res. 51(7), 1624-1642 (2010).

    6. Agbada, M.P., Brush, R.S., Mandal, N.A., et al. Role of Stargardt-3 macular dystrophy protein (ELOVL4) in the biosynthesis of very long chain fatty acids. Proc. Natl. Acad. Sci. USA 105(35), 12843-12848 (2008).