Kinase Screening Library (96-Well)

The Kinase Screening Library consists of two plates and contains approximately 160 carefully chosen selective and non-selective kinase inhibitors in a 96-well Matrix™ tube rack format as 10 mM stock solutions in DMSO. This curated library includes inhibitors of a wide range of lipid, receptor and non-receptor tyrosine, serine/threonine, and dual specificity kinases including those belonging to the ROCK, activin-like kinase (ALK), GSK3, PKC, PDGFR, VEGFR, Src, MAPK, CDK, and PI3K families, among many others. It offers expansive coverage, targeting more than 70 distinct kinases and kinase families, as well as numerous additional kinase isoforms and individual kinases within target families. Stability data is not available for individual compounds as supplied in the screening library. Panels are routinely re-evaluated to include new catalog introductions as the research evolves.

WARNING This product is not for human or veterinary use.

Minges, A., and Groth, G. Small-molecule inhibition of pyruvate phosphate dikinase targeting the nucleotide binding site. PLoS One 12(7), e0181139 (2017).

Chen, E.W., Brzostek, J., Gascoigne, N.R.J., et al. Development of a screening strategy for new modulators of T cell receptor signaling and T cell activation. Sci. Rep. 8(1), 10046 (2018).