For screening a variety of bio-active lipid compounds
Features
  • Consists of 13 plates with >820 compounds
  • Includes prostaglandins, thromboxanes, cannabinoids, D-myo-inositol-phosphates, phosphatidylinositol-phosphates, sphingolipids, ceramide derivatives, inhibitors, and receptor agonists and antagonists
  • Certain customizations available. Use the “Bulk & Custom” form to request.
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

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Bio-Active Lipid I Screening Library (96-Well)

Item No. 10506

Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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    Product Description

    The Bio-Active Lipid I Screening Library consists of 13 plates and contains more than 800 compounds in a 96-well Matrix™ tube rack format as 1.0 mM stocks in DMSO. The library may include prostaglandins, thromboxanes , cannabinoids, D-myo-inositol-phosphates, phosphatidylinositol-phosphates, sphingolipids, inhibitors, receptor agonists and antagonists, ceramide derivatives, and several other complex polyunsaturated fatty acids. This library collection is ideal for prostanoid or other G protein-coupled receptor screening, target validation, secondary screening, validating new assays and for routine pharmacological applications. Stability data is not available for individual compounds as supplied in the screening library. Panels are routinely re-evaluated to include new catalog introductions as the research evolves.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Citations

    Babcock, M.C., Mikulka, C.R., Wang, B., et alSubstrate reduction therapy for Krabbe disease and metachromatic leukodystrophy using a novel ceramide galactosyltransferase inhibitor. Sci. Rep. 11(1), 14486 (2021).

    Kwon, H.-B., Mackie, D.I., Bonnavion, R., et alThe orphan G-protein coupled receptor 182 is a negative regulator of definitive hematopoiesis through leukotriene B4 signaling. ACS Pharmacol. Transl. Sci. 3(4), 676-689 (2020).