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Naphyrone (hydrochloride)

Item № 10517
CAS № 850352-11-3
Purity ≥97%

Formulation:  A crystalline solid

     1 mg $49.00 0.00
     5 mg $135.00 0.00
     10 mg $245.00 0.00

Pricing updated 2019-06-26. Prices are subject to change without notice.

  • β-Naphyrone
  • Naphpyrovalerone
  • NRG-1
  • O-2482

Pyrovalerone is a psychoactive compound with stimulatory effects. It is a controlled drug that has been found as a contaminant in products sold as bath salts.1 Naphyrone (hydrochloride) is an analog of pyrovalerone that is characterized by the substitution of the methylphenyl group of pyrovalerone with a naphthyl group. Naphyrone potently inhibits dopamine, serotonin, and norepinephrine transporters (IC50 = 20, 33, and 136 nM, respectively).2 Naphyrone, like pyrovalerone, has been detected in bath salt-type products. This compound is intended for forensic and research purposes.

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Technical Information
Formal Name
1-(2-naphthalenyl)-2-(1-pyrrolidinyl)-1-pentanone, monohydrochloride
CAS Number
  • β-Naphyrone
  • Naphpyrovalerone
  • NRG-1
  • O-2482
Molecular Formula
C19H23NO • HCl
Formula Weight
A crystalline solid
253, 295 nm
InChI Code
InChI Key

Warning - this product is not for human or veterinary use.

Shipping & Storage
Room temperature in continental US; may vary elsewhere
≥ 2 years
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Additional Information

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References & Product Citations
Product Description References

1. Kikura-Hanajiri, R., Uchiyama, N., and Goda, Y. Survey of current trends in the abuse of psychotropic substances and plants in Japan Leg. Med. (Tokyo) 13(3), 109-115 (2011).

2. Meltzer, P.C., Butler, D., Deschamps, J.R., et al. 1-(4-methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (pyrovalerone) analogs. A promising class of monoamine uptake inhibitors J. Med. Chem. 49(4), 1420-1432 (2006).

Product Citations

Carnes, S., O'Brien, S., Szewczak, A., et al. Comparison of ultra high performance supercritical fluid chromatography, ultra high performance liquid chromatography, and gas chromatography for the separation of synthetic cathinones J. Sep. Sci. 40(17), 3545-3556 (2017).

Tremeau-Cayel, L., Carnes, S., Schandield, M.S., et al. A comparison of single quadrupole mass detection and diode array ultraviolet detection interfaced to ultra-high performance supercritical chromatography for the quantitative analysis of synthetic cathinones J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 1091, 96-100 (2018).

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