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JWH 302

Item No. 10722

Restricted Product (Schedule I)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-(3-methoxyphenyl)-1-(1-pentyl-1H-indol-3-yl)-ethanone
CAS Number
864445-45-4
Molecular Formula
C22H25NO2
Formula Weight
335.4
Purity
≥95%
Formulation
A 50 mg/ml solution in methyl acetate
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlEthanol:PBS (pH 7.2) (1:2): 0.33 mg/ml
λmax
210, 245, 306 nm
SMILES
O=C(CC1=CC(OC)=CC=C1)C2=CN(CCCCC)C3=CC=CC=C32
InChi Code
InChI=1S/C22H25NO2/c1-3-4-7-13-23-16-20(19-11-5-6-12-21(19)23)22(24)15-17-9-8-10-18(14-17)25-2/h5-6,8-12,14,16H,3-4,7,13,15H2,1-2H3
InChi Key
XZVYWLVYUAQEIM-UHFFFAOYSA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $77

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    10 mg

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    25 mg

    $339

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    Product Description

    JWH 302 (Item No. 10722) is a cannabimimetic indole that shows 5-fold selectivity for the central cannabinoid (CB1) receptor with a Ki value of 17 nM compared to the peripheral cannabinoid (CB2) receptor (Ki = 89 nM).1 JWH 302 stimulates GTPγS binding of CB1 and CB2 receptors with EC50 values of 29.3 and 24.4 nM, respectively.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Huffman, J.W., Szklennik, P.V., Almond, A., et al. 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles. Bioorg. Med. Chem. Lett. 15(18), 4110-4113 (2005).

    Product Citations

    Ciolino, L.A. Quantitation of synthetic cannabinoids in plant materials using high performance liquid chromatography with UV detection (validated method). J. Forensic Sci. 60(5), 1171-1181 (2015).