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JWH 147

Item No. 10826

Restricted Product (Schedule I)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(1-hexyl-5-phenyl-1H-pyrrol-3-yl)-1-naphthalenyl-methanone
CAS Number
914458-20-1
Molecular Formula
C27H27NO
Formula Weight
381.5
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mlDMSO: 10 mg/mlEthanol: 10 mg/ml
λmax
217, 254 nm
SMILES
O=C(C1=CN(CCCCCC)C(C2=CC=CC=C2)=C1)C3=C(C=CC=C4)C4=CC=C3
InChi Code
InChI=1S/C27H27NO/c1-2-3-4-10-18-28-20-23(19-26(28)22-13-6-5-7-14-22)27(29)25-17-11-15-21-12-8-9-16-24(21)25/h5-9,11-17,19-20H,2-4,10,18H2,1H3
InChi Key
FRMYAMAGHYHNKF-UHFFFAOYSA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

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    25 mg

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    Product Description

    JWH 147 (Item No. 10826) is a synthetic cannabinoid (CB) with a high affinity for both the central CB1 receptor (Ki = 11 nM) and the peripheral CB2 receptor (Ki = 7.1 nM).1 Its physiological properties have not been elucidated. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Huffman, J.W., Padgett, L.W., Isherwood, M.L., et al. 1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: New high affinity ligands for the cannabinoid CB1 and CB2 receptors. Bioorg. Med. Chem. Lett. 16(20), 5432-5435 (2006).

    Product Citations

    Mercier, G., Mohamed, K.A., Zagzoog, A., et al. In vitro pharmacological activity of twenty-eight synthetic cannabinoid receptor agonists at the type 1 and 2 cannabinoid receptors. Neurochem. Int. 190, 106039 (2025).

    Ciolino, L.A. Quantitation of synthetic cannabinoids in plant materials using high performance liquid chromatography with UV detection (validated method). J. Forensic Sci. 60(5), 1171-1181 (2015).