For immunochemical analysis of SMAD4
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SMAD4 Polyclonal Antibody

Item No. 10838

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Immunogen
synthetic peptides corresponding to amino acids 186-199 and 509-523 of human SMAD4
Amino Acids
(PSNRASTETYSTPA) and (PSNRASTETYSTPA)
Formulation (Request formulation change)
100 µg of protein G-purified IgG in 200 µl PBS containing 0.2% gelatin and 0.05% sodium azide
Host
Rabbit
Applications
WB
Species Reactivity
(+) Human SMAD4(+) Mouse SMAD4(+) New World monkey SMAD4(+) Rat SMAD4
Origin
Animal/Rabbit
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    100 µg

    $343

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    Product Description

    SMADs are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor β superfamily.1 SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, SMAD2, SMAD3, SMAD5, SMAD8, and SMAD9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and SMAD7). SMAD1, SMAD5, SMAD8, and SMAD9 have high degrees of homology and antibodies are available that recognize sequences common to all of them. SMAD8 and SMAD9 are typically used as alternate names for one another in the literature.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Topper, J.N., Cai, J., and Qui, Y. Vascular MADs: Two novel MAD-related genes selectively inducible by flow in human vascular endothelium. Proc. Natl. Acad. Sci. USA 94(17), 9314-9319 (1997).