For immunochemical analysis of SMAD6
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SMAD6 Polyclonal Antibody

Item No. 10839

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Immunogen
synthetic peptides corresponding to amino acids 85-99 and amino acids 372-388 of human SMAD6
Amino Acids
(RAGGPPRPMSEPGAG) and (NLEQRSESVRRTRSKIG)
Formulation (Request formulation change)
100 µg protein G-purified in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide
Host
Rabbit
Applications
IHC and WB
Species Reactivity
(+) Human SMAD6(+) Mouse SMAD6(+) New World Monkey SMAD6(+) Ovine SMAD6(+) Rat SMAD6
Origin
Animal/Rabbit
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    100 µg

    $340

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    Product Description

    SMADs are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor β superfamily.1 SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, SMAD2, SMAD3, SMAD5, SMAD8, and SMAD9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and SMAD7). SMAD1, SMAD5, SMAD8, and SMAD9 have high degrees of homology and antibodies are available that recognize sequences common to all of them. SMAD8 and SMAD9 are typically used as alternate names for one another in the literature.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Kawai, S., Faucheu, S., Gallea, S., et al. Mouse Smad8 phosphorylation downstream of BMP receptors ALK-2, ALK-3, and ALK-6 induces its association with Smad4 and transcriptional activity. Biochem. Biophys. Res. Commun. 271(3), 682-687 (2000).