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JWH 122 N-(5-hydroxypentyl) metabolite

Item No. 10925

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • MAM2201 N-(5-hydroxypentyl) metabolite
Technical Information
Formal Name
[1-(5-hydroxypentyl)-1H-indol-3-yl](4-methyl-1-naphthalenyl)-methanone
CAS Number
1379604-68-8
Molecular Formula
C25H25NO2
Formula Weight
371.5
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 12.5 mg/mlEthanol: 10 mg/ml
λmax
222, 315 nm
SMILES
O=C(C1=CC=C(C)C2=C1C=CC=C2)C3=CN(CCCCCO)C4=C3C=CC=C4
InChi Code
InChI=1S/C25H25NO2/c1-18-13-14-22(20-10-4-3-9-19(18)20)25(28)23-17-26(15-7-2-8-16-27)24-12-6-5-11-21(23)24/h3-6,9-14,17,27H,2,7-8,15-16H2,1H3
InChi Key
JRALTDRFXRCGRH-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    JWH 122 is a synthetic cannabinoid (CB) of the naphthoylindole class that is structurally related to JWH 018 and JWH 073. It displays high-affinities for both CB1 (Ki = 0.69 nM) and CB2 (Ki = 1.2 nM) receptors.1,2 JWH 122 N-(5-hydroxypentyl) metabolite is a metabolite of JWH 122 (Item No. 10591) that is characterized by monohydroxylation of the N-alkyl chain. Currently, there are no reports of its biological activity.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ernst, L., Schiebel, H.M., Theuring, C., et al. Identification and characterization of JWH-122 used as new ingredient in "spice-like" herbal incenses. Forensic Sci. Int. 208(1-3), e31-e35 (2011).

    2. Kikura-Hanajiri, R., Uchiyama, N., and Goda, Y. Survey of current trends in the abuse of psychotropic substances and plants in Japan. Leg. Med. (Tokyo) 13(3), 109-115 (2011).

    Product Citations

    Cho, B., Cho, H.S., Kim, J., et al. Simultaneous determination of synthetic cannabinoids and their metabolites in human hair using LC-MS/MS and application to human hair. Forensic Sci. Int. 306, 110058 (2020).

    Hutter, M., Broecker, S., Kneisel, S., et al. Metabolism of synthetic cannabinoid receptor agonists encountered in clinical casework: Major in vivo phase I metabolites of JWH-007, JWH-019, JWH-203, JWH-307, UR-144, XLR-11, AM-2201, MAM-2201 and AM-694 inhuman urine using LC-MS/MS. Curr. Pharm. Biotechnol. 19(2), 144-162 (2018).