An N-acylethanolamine signaling molecule
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Palmitoleoyl Ethanolamide

Item No. 10965

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(2-hydroxyethyl)-9Z-hexadecenamide
CAS Number
94421-67-7
Synonyms
  • POEA
Molecular Formula
C18H35NO2
Formula Weight
297.5
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 100 mg/mlDMSO: 100 mg/mlEthanol: 100 mg/mlPBS (pH 7.2): <100 µg/ml
SMILES
CCCCCC/C=C\CCCCCCCC(NCCO)=O
InChi Code
InChI=1S/C18H35NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)19-16-17-20/h7-8,20H,2-6,9-17H2,1H3,(H,19,21)/b8-7-
InChi Key
WFRLANWAASSSFV-FPLPWBNLSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    5 mg

    $69

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    10 mg

    $127

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    50 mg

    $525

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    100 mg

    $918

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    Product Description

    N-acylethanolamines (NAEs) are lipid-derived signaling compounds. For example, arachidonoyl ethanolamide is an endogenous cannabinoid (CB) that activates the CB1 and CB2 receptors. Palmitoleoyl Ethanolamide (POEA) is an NAE that is produced endogenously from palmitoleic acid.1 Unlike arachidonoyl ethanolamide and palmitoyl ethanolamide, POEA does not have antinociceptive effects, as assessed in the formalin-evoked pain model.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lucanic, M., Held, J.M., Vantipalli, M.C., et al. N-acylethanolamine signalling mediates the effect of diet on lifespan in Caenorhabditis elegans. Nature 473(7346), 226-229 (2011).

    2. Calignano, A., LaRana, G., and Piomelli, D. Antinociceptive activity of the endogenous fatty acid amide, palmitylethanolamide. Eur. J. Pharmacol. 419(2-3), 191-198 (2001).