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JWH 018 N-(5-bromopentyl) analog

Item № 11047
CAS № 1445578-62-0
Purity ≥98%
product image
                (CAS 1445578-62-0)

Formulation:  A crystalline solid

SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     1 mg $65.00 0.00
     5 mg $293.00 0.00
     10 mg $520.00 0.00

Pricing updated 2019-03-26. Prices are subject to change without notice.

Description

JWH 018 is a synthetic cannabinoid (CB) that potently activates the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors (Ki = 9.0 and 2.94 nM, respectively).1 This cannabimimetic compound has frequently been found in herbal blends.2,3,4 JWH 018 N-(5-bromopentyl) analog differs structurally from JWH 018 by having bromine added at the 5 position of the pentyl chain. The biological activities of this compound have not been characterized. This product is intended for forensic and research applications.

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Technical Information
Formal Name
(1-(5-bromopentyl)-1H-indol-3-yl)(naphthalen-1-yl)methanone
CAS Number
1445578-62-0
Molecular Formula
C24H22BrNO
Formula Weight
420.3
Purity
≥98%
Formulation
A crystalline solid
λmax
219, 247, 314 nm
SMILES
O=C(C1=CC=CC2=C1C=CC=C2)C3=CN(CCCCCBr)C4=CC=CC=C43
InChI Code
InChI=1S/C24H22BrNO/c25-15-6-1-7-16-26-17-22(20-12-4-5-14-23(20)26)24(27)21-13-8-10-18-9-2-3-11-19(18)21/h2-5,8-14,17H,1,6-7,15-16H2
InChI Key
QDWNXDILPHVKLY-UHFFFAOYSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
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Additional Information

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References & Product Citations
Product Description References

1. Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding Drug Alcohol Depend. 60(2), 133-140 (2000).

2. Auwärter, V., Dresen, S., Weinmann, W., et al. “Spice” and other herbal blends: Harmless incense or cannabinoid designer drugs? Journal of Mass Spectrometry 44, 832-837 (2009).

3. Lindigkeit, R., Boehme, A., Eiserloh, I., et al. Spice: A never ending story? Forensic Science International 191, 58-63 (2009).

4. Uchiyama, N., Kikura-Hanajiri, R., Kawahara, N., et al. Identification of a cannabimimetic indole as a designer drug in a herbal product Forensic Toxicol. 27, 61-66 (2009).

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