A non-enzymatic dehydration product of PGE1
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Prostaglandin B1

Item No. 11110

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9-oxo-15S-hydroxy-prosta-8(12),13E-dien-1-oic acid
CAS Number
13345-51-2
Synonyms
  • PGB1
Molecular Formula
C20H32O4
Formula Weight
336.5
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: >75 mg/mlDMSO: >50 mg/mlEthanol: >100 mg/mlPBS (pH 7.2): >2 mg/ml
λmax
278 nm
SMILES
O=C1C(CCCCCCC(O)=O)=C(/C=C/[C@@H](O)CCCCC)CC1
InChi Code
InChI=1S/C20H32O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h12,14,17,21H,2-11,13,15H2,1H3,(H,23,24)/b14-12+/t17-/m0/s1
InChi Key
YBHMPNRDOVPQIN-VSOYFRJCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

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    Product Description

    Prostaglandin B1 (PGB1) is a non-enzymatic dehydration product of PGE1 resulting from treatment with strong base. Oligomers of PGB1 are known to exhibit antioxidant and ionophoric activity.1,2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Uribe, S., Ohnishi, S.T., Israelite, C., et al. Calcium ionophoretic activity of chemically synthesized oligomeric derivatives of prostaglandin B1. Biochim. Biophys. Acta 924(1), 87-98 (1987).

    2. Ohnishi, S.T., and Devlin, T.M. Calcium ionophore activity of a prostaglandin B1 derivative (PGBχ). Biochem. Biophys. Res. Commun. 89(1), 240-245 (1979).

    3. Hamberg, M. Metabolism of prostaglandin in rat liver mitochondria. Eur. J. Biochem. 6(1), 135-146 (1968).