An intermediate in the β-oxidation of palmitic acid
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Δ2-trans-Hexadecenoic Acid

Item No. 11132

Technical Information
Formal Name
2E-hexadecenoic acid
CAS Number
929-79-3
Synonyms
  • FA 16:1
Molecular Formula
C16H30O2
Formula Weight
Purity
≥95%
A crystalline solid
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlEthanol:PBS (pH7.2) (1:7): 0.25 mg/ml
SMILES
CCCCCCCCCCCCC/C=C/C(O)=O
InChi Code
InChI=1S/C16H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h14-15H,2-13H2,1H3,(H,17,18)/b15-14+
InChi Key
ZVRMGCSSSYZGSM-CCEZHUSRSA-N
Side Chain Carbon Sum
16:1
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Formation of cis monoenoic acids from unsaturated fatty acids, such as palmitoleic acid (9-cis-hexadecenoic acid) from palmitic acid occurs readily in animal tissues.1 Δ2-trans-Hexadecenoic acid is an intermediate formed in the β-oxidation of palmitic acid.2 In a model meant to simulate gastric ulceration, Δ2-trans-hexadecenoic acid at 10 mg/kg significantly inhibits gastric juice secretion in pylorus-ligated rats.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nakano, M., and Fujino, Y. Enzymatic formation of hexadecenoic acid from palmitic acid. Agr. Biol. Chem. 39(3), 707-710 (1975).

    2. Jones, J.A., and Blecher, M. Synthesis and characterization of 3-ketohexadecanoic acid-1-14C, DL-3-hydroxyhexadecanoic acid-1-14C, and trans-2-hexadecenoic acid-1-14C. J. Lipid Res. 7(3), 422-426 (1966).

    3. Mimura, T., Kohda, I., Maeda, K., et alInhibitory effects of unsaturated fatty acids of trans-2-C10:1 to trans-2-C16:1 several C18:n and C20:n on gastric secretion and experimental ulceration in rats. J. Pharmacobiodyn. 6(8), 527-538 (1983).