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4-hydroxy MET

Item No. 11148

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • 4-HO MET
  • 4-hydroxy-N-methyl-N-Ethyltryptamine
  • Metocin
Technical Information
Formal Name
3-[2-(ethylmethylamino)ethyl]-1H-indol-4-ol
CAS Number
77872-41-4
Molecular Formula
C13H18N2O
Formula Weight
218.3
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlDMSO:PBS(pH7.2) (1:1): 0.5 mg/mlEthanol: 0.5 mg/ml
λmax
223, 269, 286, 295 nm
SMILES
CN(CC)CCC1=CNC2=C1C(O)=CC=C2
InChi Code
InChI=1S/C13H18N2O/c1-3-15(2)8-7-10-9-14-11-5-4-6-12(16)13(10)11/h4-6,9,14,16H,3,7-8H2,1-2H3
InChi Key
ORWQBKPSGDRPPA-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    4-hydroxy MET (Item No. 11148) is an analytical reference standard categorized as a tryptamine.1 4-hydroxy MET induces the head-twitch response (HTR) in mice. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Klein, A.K., Chatha, M., Laskowski, L.J., et al. Investigation of the structure−activity relationships of psilocybin analogues. ACS Pharmacol. Transl. Sci. 4(2), 533-542 (2020).

    Product Citations

    Barovic, A., Pittiglio, M.K., Barrett, J.M., et al. Presence of 4‑hydroxy‑N‑methyl‑N‑ethyltryptamine in commercially available products. ACS Omega 11(2), 3448-3454 (2026).

    Kozell, L.B., Eshleman, A.J., Swanson, T.L., et al. Pharmacologic activity of substituted tryptamines at 5-HT2AR, 5-HT2CR, 5-HT1AR, and SERT. J. Pharmacol. Exp. Ther. JPET-AR-2022-001454 (2023).

    Castleberry, T.A., Lu, B., Smock, S.L., et al. Molecular cloning and functional charcterization of the canine prostaglandin E2 receptor EP4 subtype. Prostaglandins Other Lipid Mediat. 65(4), 167-187 (2001).