A fluorescent H2S probe
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WSP-1

Item No. 11179

Technical Information
Formal Name
3'-methoxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-6'-yl 2-(pyridin-2-yldisulfanyl)benzoate
CAS Number
1352750-34-5
Synonyms
  • Washington State Probe-1
Molecular Formula
C33H21NO6S2
Formula Weight
Purity
≥95%
Emission
515 nm
Excitation
465 nm
A crystalline solid
DMF: 20 mg/mlDMSO: 2 mg/ml
λmax
225 nm
SMILES
O=C(OC1=CC=C2C(OC3=C(C24C5=CC=CC=C5C(O4)=O)C=CC=C3)=C1)CO=C(OC1=CC=C2C(OC3=C(C24C5=CC=CC=C5C(O4)=O)C=CC(OC)=C3)=C1)C6=C(SSC7=NC=CC=C7)C=CC=C6
InChi Code
InChI=1S/C33H21NO6S2/c1-37-20-13-15-25-27(18-20)39-28-19-21(14-16-26(28)33(25)24-10-4-2-8-22(24)32(36)40-33)38-31(35)23-9-3-5-11-29(23)41-42-30-12-6-7-17-34-30/h2-19H,1H3
InChi Key
VHKQAUGSGQUCDU-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    WSP-1 is a reactive disulfide-containing, fluorescent probe designed to detect H2S in biological samples and cells. Through a reaction-based fluorescent turn-on strategy, WSP-1 selectively and rapidly reacts with H2S to generate benzodithiolone and a fluorophore with excitation and emission maxima of 465 and 515 nm, respectively.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Liu, C., Pan, J., Li, S., et alCapture and visualization of hydrogen sulfide via a fluorescent probe. Angew. Chem. Int. Ed. Engl. 50(44), 10327-10329 (2011).

    Product Citations

    Zhou, Y., Mazur, F., Liang, K., et alSensitivity and selectivity analysis of fluorescent probes for hydrogen sulfide detection. Chem. Asian J. 17(5), e202101399 (2022).