A fatty acid amide that protects against ER stress-dependent cell death
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Termitomycamide E

Item No. 11191

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[2-(4-hydroxyphenyl)ethyl]-9Z,12Z-octadecadienamide
CAS Number
1177258-62-6
Synonyms
  • 2'-Deoxotermitomycamide A
Molecular Formula
C26H41NO2
Formula Weight
399.6
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlEthanol:PBS (pH7.2)(1:20): 0.05 mg/ml
λmax
225, 279, 349 nm
SMILES
CCCCC/C=C\C/C=C\CCCCCCCC(NCCC1=CC=C(O)C=C1)=O
InChi Code
InChI=1S/C26H41NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-26(29)27-23-22-24-18-20-25(28)21-19-24/h6-7,9-10,18-21,28H,2-5,8,11-17,22-23H2,1H3,(H,27,29)/b7-6-,10-9-
InChi Key
JTSNNDBVDQFVEG-HZJYTTRNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    5 mg

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    50 mg

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    Product Description

    Endoplasmic reticulum (ER) stress, caused by accumulation of misfolded proteins and a disruption of calcium homeostasis, has been linked to several neuronal diseases including, Parkinson’s, Alzheimer’s, and prion diseases. A screen for protective activity against ER stress-dependent cell death identified termitomycamides, extracts from the fruiting bodies of T. titanicus, a notably large edible mushroom that is cultivated symbiotically in the nests of termites. Termitomycamide E is a fatty acid isolated from T. titanicus that at a dose of 0.1 μg/ml protects against ER stress-dependent cell death in Neuro2a cells induced by tunicamycin.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Choi, J.H., Maeda, K., Nagai, K., et al. Termitomycamides A to E, fatty acid amides isolated from the mushroom Termitomyces titanicus, suppress endoplasmic reticulum stress. Org. Lett. 12(21), 5012-5015 (2010).