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JWH 175

Item No. 11201

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-(1-naphthalenylmethyl)-1-pentyl-1H-indole
CAS Number
619294-35-8
Molecular Formula
C24H25N
Formula Weight
327.5
Purity
≥98%
Formulation
A solution in acetonitrile
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlEthanol: 20 mg/ml
λmax
223, 283 nm
SMILES
CCCCCN1C2=CC=CC=C2C(CC3=CC=CC4=C3C=CC=C4)=C1
InChi Code
InChI=1S/C24H25N/c1-2-3-8-16-25-18-21(23-14-6-7-15-24(23)25)17-20-12-9-11-19-10-4-5-13-22(19)20/h4-7,9-15,18H,2-3,8,16-17H2,1H3
InChi Key
TYBRSILIYTUTSQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $77

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    $145

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    Cayman Chemical
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    Product Description

    JWH 175 is a synthetic cannabinoid (CB) that potently activates the central CB1 receptor (Ki = 22 nM).1 As a naphthylmethylindole, it is structurally related to JWH 018. The properties of this compound at the peripheral CB2 receptor or in vivo have not been characterized. This product is intended for forensic and research purposes.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Huffman, J.W., Mabon, R., Wu, M.J., et al. 3-indolyl-1-naphthylmethanes: New cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor. Bioorgan. Med. Chem. 11(4), 539-549 (2003).

    Product Citations

    Mercier, G., Mohamed, K.A., Zagzoog, A., et al. In vitro pharmacological activity of twenty-eight synthetic cannabinoid receptor agonists at the type 1 and 2 cannabinoid receptors. Neurochem. Int. 190, 106039 (2025).

    Ciolino, L.A. Quantitation of synthetic cannabinoids in plant materials using high performance liquid chromatography with UV detection (validated method). J. Forensic Sci. 60(5), 1171-1181 (2015).