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Phenylpiperazine (hydrochloride)

Item No. 11203

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • NSC 38914
  • NSC 150847
Technical Information
Formal Name
1-phenyl-piperazine, dihydrochloride
CAS Number
4004-95-9
Molecular Formula
C10H14N2 • 2HCl
Formula Weight
235.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mlDMSO: 30 mg/mlEthanol: 2 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
243 nm
SMILES
N1(C2=CC=CC=C2)CCNCC1.Cl.Cl
InChi Code
InChI=1S/C10H14N2.2ClH/c1-2-4-10(5-3-1)12-8-6-11-7-9-12;;/h1-5,11H,6-9H2;2*1H
InChi Key
CUTPTQNQXVVRDB-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Phenylpiperazine is the base compound from which a broad series of bioactive products are derived. Many are entactogenic drugs which induce central serotonin release.1,2,3 Substituted phenylpiperazines, such as 1-(3-chlorophenyl)piperazine, have been identified as designer drugs or drugs of abuse.4,5 This product is intended for forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Eriksson, E., Engberg, G., Bing, O., et al. Effects of mCPP on the extracellular concentrations of serotonin and dopamine in rat brain. Neuropsychopharmacology 20(3), 287-296 (1999).

    2. Baumann, M.H., Clark, R.D., Budzynski, A.G., et al. N-substituted piperazines abused by humans mimic the molecular mechanism of 3,4-methylenedioxymethamphetamine (MDMA, or “Ecstasy”). Neuropsychopharmacology 30(3), 550-560 (2005).

    3. Hill, S.L., and Thomas, S.H. Clinical toxicology of newer recreational drugs. Clin. Toxicol. (Phila) 49(8), 705-719 (2011).

    4. Nagai, F., Nonaka, R., and Satoh Hisashi Kamimura, K. The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain. Eur. J. Pharmacol. 559(2-3), 132-137 (2007).

    5. Arbo, M.D., Bastos, M.L., and Carmo, H.F. Piperazine compounds as drugs of abuse. Drug Alcohol Depend. 122(3), 174-185 (2012).