1-(3-Trifluoromethylphenyl)piperazine (hydrochloride) (CAS 76835-14-8) | Cayman Chemical
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1-(3-Trifluoromethylphenyl)piperazine (hydrochloride)

Item № 11205
CAS № 76835-14-8
Purity ≥98%
product image
                (CAS 76835-14-8)

Formulation:  A crystalline solid

SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     10 mg $35.00 0.00
     50 mg $81.00 0.00
     100 mg $144.00 0.00

Pricing updated 2018-07-16. Prices are subject to change without notice.

Description
Synonyms
  • TFMPP
  • 1-(m-Trifluoromethylphenyl)piperazine
  • 1-(meta-Trifluoromethylphenyl)piperazine

1-(3-Trifluoromethylphenyl)piperazine (TFMPP) is an entactogenic drug which selectively promotes the release of serotonin.1 When used in combination with 1-benzylpiperazine, TFMPP increases both serotonin and dopamine, mirroring the effects of 3,4-methylenedioxymethamphetamine.1 Drug-drug synergism may induce seizures.1 TFMPP has been identified in party pills and powders.2,3 Its metabolism in rats has been described.4 This product is intended for forensic applications.

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Technical Information
Formal Name
1-[3-(trifluoromethyl)phenyl]-piperazine, dihydrochloride
CAS Number
76835-14-8
Synonyms
  • TFMPP
  • 1-(m-Trifluoromethylphenyl)piperazine
  • 1-(meta-Trifluoromethylphenyl)piperazine
Molecular Formula
C11H13F3N2 • 2HCl
Formula Weight
303.2
Purity
≥98%
Formulation
A crystalline solid
λmax
249, 293 nm
SMILES
FC(C1=CC=CC(N2CCNCC2)=C1)(F)F.Cl.Cl
InChI Code
InChI=1S/C11H13F3N2.2ClH/c12-11(13,14)9-2-1-3-10(8-9)16-6-4-15-5-7-16;;/h1-3,8,15H,4-7H2;2*1H
InChI Key
JCUKFOWDFVZILY-UHFFFAOYSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 2 years
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Additional Information

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References & Product Citations
Product Description References

1. Baumann, M.H., Clark, R.D., Budzynski, A.G., et al. N-substituted piperazines abused by humans mimic the molecular mechanism of 3,4-methylenedioxymethamphetamine (MDMA, or “Ecstasy”). Neuropsychopharmacology 30(3), 550-560 (2005).

2. Hill, S.L., and Thomas, S.H. Clinical toxicology of newer recreational drugs. Clin.Toxicol.(Phila) 49(8), 705-719 (2011).

3. Arbo, M.D., Bastos, M.L., and Carmo, H.F. Piperazine compounds as drugs of abuse. Drug Alcohol Depend. 122(3), 174-185 (2012).

4. Staack, R.F., and Maurer, H.H. Metabolism of designer drugs of abuse. Curr.Drug Metab. 6(3), 259-274 (2005).

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