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4-hydroxy DiPT (hydrochloride)

Item No. 11312

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • 4-hydroxy-N,N-Diisopropyltryptamine
Technical Information
Formal Name
3-[2-[bis(1-methylethyl)amino]ethyl]-1H-indol-4-ol, monohydrochloride
CAS Number
63065-90-7
Molecular Formula
C16H24N2O • HCl
Formula Weight
296.8
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 0.1 mg/mlDMSO: 3 mg/mlDMSO:PBS(pH7.2) (1:1): 0.5 mg/mlMethanol: 1 mg/ml
λmax
222, 267, 293 nm
SMILES
CC(C)N(C(C)C)CCC1=CNC2=C1C(O)=CC=C2.Cl
InChi Code
InChI=1S/C16H24N2O.ClH/c1-11(2)18(12(3)4)9-8-13-10-17-14-6-5-7-15(19)16(13)14;/h5-7,10-12,17,19H,8-9H2,1-4H3;1H
InChi Key
SBBDIXSABJRYFC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    4-hydroxy DiPT (hydrochloride) (Item No. 11312) is an analytical reference standard categorized as a tryptamine.1 4-hydroxy DiPT induces the head-twitch response (HTR) in mice, indicating hallucinogenic potential, and substitutes for the amphetamine DOM in a two-lever drug discrimination test in rats.2,3 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Rickli, A., Moning, O.D., Hoener, M.C., et al. Receptor interaction profiles of novel psychoactive tryptamines compared with classic hallucinogens. Eur. Neuropsychopharmacol. 26(8), 1327-1337 (2016).

    2. Klein, A.K., Chatha, M., Laskowski, L.J., et al. Investigation of the structure−activity relationships of psilocybin analogues. ACS Pharmacol. Transl. Sci. 4(2), 533-542 (2020).

    3. Gatch, M.B., Hoch, A., and Carbonaro, T.M. Discriminative stimulus effects of substituted tryptamines in rats. ACS Pharmacol. Transl. Sci. 4(2), 467-471 (2020).

    Product Citations

    Kozell, L.B., Eshleman, A.J., Swanson, T.L., et al. Pharmacologic activity of substituted tryptamines at 5-HT2AR, 5-HT2CR, 5-HT1AR, and SERT. J. Pharmacol. Exp. Ther. JPET-AR-2022-001454 (2023).

    Kimoto, T., Tsurugizawa, T., Ohta, Y., et al. Neurosteroid synthesis by cytochrome P450-containing systems localized in the rat brain hippocampal neurons: N-methyl-D-aspartate and calcium-dependent synthesis. Endocrinology 142(8), 3578-3589 (2001).