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2C-B-FLY (hydrochloride)

Item No. 11473

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
8-bromo-2,3,6,7-tetrahydro-benzo[1,2-b:4,5-b']difuran-4-ethanamine, monohydrochloride
CAS Number
178557-21-6
Molecular Formula
C12H14BrNO2 • HCl
Formula Weight
320.6
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 1 mg/mlDMSO: 5 mg/mlDMSO:PBS(pH7.2) (1:1): 0.5 mg/mlMethanol: 1 mg/ml
λmax
203, 315 nm
SMILES
BrC1=C2C(OCC2)=C(CCN)C3=C1OCC3.Cl
InChi Code
InChI=1S/C12H14BrNO2.ClH/c13-10-9-3-6-15-11(9)7(1-4-14)8-2-5-16-12(8)10;/h1-6,14H2;1H
InChi Key
XHRNOQRXDGETTA-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

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    1 mg

    $90

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    5 mg

    $392

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    10 mg

    $696

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    Cayman Chemical
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    Product Description

    2C-B-FLY is the dihydrodifuran analog of the Schedule I hallucinogen 4-bromo-2,5-dimethoxyphenethylamine (2C-B).1,2 It is expected to show similar activity to 2C-B, which acts as a partial agonist at the 5-HT2A serotonin receptor and demonstrates high binding affinity for the 5-HT2B and 5-HT2C serotonin receptors.3,4 This product is intended for forensic and research purposes.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Reed, E.C., and Kiddon, G.S. The characterization of three fly compounds (2C-B-FLY, 3C-B-FLY, and Bromo-Dragon FLY). Microgram J. 5(1-4), 1-8 (2007).

    2. Pichini, S., Pujadas, M., Marchei, E., et al. Liquid chromatography-atmospheric pressure ionization electrospray mass spectrometry determination of "hallucinogenic designer drugs" in urine of consumers. J. Pharm. Biomed. Anal. 47(2), 335-342 (2008).

    3. Monte, A.P., Marona-Lewicka, D., Parker, M.A., et al. Dihydrobenzofuran analogues of hallucinogens. 3. Models of 4-substituted (2,5-dimethoxyphenyl)alkylamine derivatives with rigidified methoxy groups. J. Med. Chem. 39(15), 2953-2961 (1996).

    4. Chambers, J.J., Kurrasch-Orbaugh, D.M., Parker, M.A., et al. Enantiospecific synthesis and pharmacological evaluation of a series of super-potent, conformationally restricted 5-HT2A/2C receptor agonists. J. Med. Chem. 44(6), 1003-1010 (2001).