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5-methoxy AMT

Item No. 11553

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • 5-MeO AMT
Technical Information
Formal Name
5-methoxy-α-methyl-1H-indole-3-ethanamine
CAS Number
1137-04-8
Molecular Formula
C12H16N2O
Formula Weight
204.3
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mlDMSO: 16 mg/mlDMSO:PBS(pH7.2) (1:1): 0.5 mg/mlEthanol: 14 mg/mlMethanol: 1 mg/ml
λmax
223, 278 nm
SMILES
CC(N)CC1=CNC2=CC=C(OC)C=C21
InChi Code
InChI=1S/C12H16N2O/c1-8(13)5-9-7-14-12-4-3-10(15-2)6-11(9)12/h3-4,6-8,14H,5,13H2,1-2H3
InChi Key
OGNJZVNNKBZFRM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $62

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    10 mg

    $94

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    25 mg

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    Cayman Chemical
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    Product Description

    5-methoxy AMT (5-MeO AMT) is a potent psychoactive analog of 5-methoxy DiPT (Item No. 11865) and α-methyltryptamine (AMT), tryptamine derivatives that inhibit reuptake and stimulate release of monoamines.1 5-MeO AMT inhibits re-uptake (IC50s = 0.18, 2.9, and 3.37 μM) and stimulates release (EC50s = 1.5, 460, and 8.9 μM) of dopamine, serotonin, and norepinephrine, respectively from rat brain synaptosomes.1 5-MeO AMT, sometimes called Alpha-O, has been sold under the guise of LSD and abused as a recreational drug.2 This tryptamine analog is intended only to be used to aid the forensic analysis of samples that may contain this compound or for scientific research applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nagai, F., Nonaka, R., and Satoh Hisashi Kamimura, K. The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain. Eur. J. Pharmacol. 559(2-3), 132-137 (2007).

    2. Zimmerman, M.M. The identification of 5-methoxy-alpha-methyltryptamine (5-MeO-AMT). (2012).

    Product Citations

    Ruiu, S., Pinna, G.A., Marchese, G., et al. Synthesis and characterization of NESS 0327: A novel putative antagonist of the CB1 cannabinoid receptor. J. Pharmacol. Exp. Ther. 306(1), 363-370 (2003).