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N,N-DMA (hydrochloride)

Item No. 11556

Restricted Product (Schedule I)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • Dimetamfetamine
  • N,N-Dimethylamphetamine
  • Metrotonin
  • NSC 27146
  • NSC 75736
  • T 312
Technical Information
Formal Name
N,N,α-trimethyl-benzeneethanamine, monohydrochloride
CAS Number
33286-27-0
Molecular Formula
C11H17N • HCl
Formula Weight
199.7
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 3 mg/mlDMSO: 5 mg/mlEthanol: 20 mg/mlPBS (pH 7.2): 5 mg/ml
SMILES
CC(N(C)C)CC1=CC=CC=C1.Cl
InChi Code
InChI=1S/C11H17N.ClH/c1-10(12(2)3)9-11-7-5-4-6-8-11;/h4-8,10H,9H2,1-3H3;1H
InChi Key
UTWYKDPIWNRKCN-UHFFFAOYSA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $49

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    10 mg

    $93

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    50 mg

    $376

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    Product Description

    N,N-Dimethylamphetamine (N,N-DMA) is a regulated stimulant that is an N-methylated analog of methamphetamine.1 It is often found as an impurity in preparations of methamphetamine.2,3 DMA itself is less active and less neurotoxic than methamphetamine.1,4 The metabolites of DMA that are detectable in human urine have been characterized.5,6 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Witkin, J.M., Ricaurte, G.A., and Katz, J.L. Behavioral effects of N-methylamphetamine and N,N-dimethylamphetamine in rats and squirrel monkeys. J. Pharmacol. Exp. Ther. 253(2), 466-474 (1990).

    2. Kuwayama, K., Tsujikawa, K., Miyaguchi, H., et al. Identification of impurities and the statistical classification of methamphetamine using headspace solid phase microextraction and gas chromatography-mass spectrometry. Forensic Sci. Int. 160(1), 44-52 (2006).

    3. Qi, Y., Evans, I.D., and McCluskey, A. Australian Federal Police seizures of illicit crystalline methamphetamine (“ice”) 1998-2002: Impurity analysis. Forensic Sci. Int. 164(2-3), 201-210 (2006).

    4. Yao, B.B., Hsieh, G.C., Frost, J.M., et al. In vitro and in vivo characterization of A-796260: A selective cannabinoid CB2 receptor agonist exhibiting analgesic activity in rodent pain models. Br. J. Pharmacol. 153(2), 390-401 (2008).

    5. Sato, M., Hida, M., and Nagase, H. Analysis of dimethylamphetamine and its metabolites in human urine by liquid chromatography-electrospray ionization-mass spectrometry with direct sample injection. Forensic Sci. Int. 128(3), 146-154 (2002).

    6. Katagi, M., Tatsuno, M., Miki, A., et al. Discrimination of dimethylamphetamine and methamphetamine use: Simultaneous determination of dimethylamphetamine-N-oxide and other metabolites in urine by high-performance liquid chromatography-electrospray ionization mass spectrometry. J. Anal. Toxicol. 24(5), 354-358 (2000).