An antifungal agent
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Labeled Version(s)
18252Fluconazole-d4
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Fluconazole

Item No. 11594

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
α-(2,4-difluorophenyl)-α-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazole-1-ethanol
CAS Number
86386-73-4
Synonyms
  • UK 49858
Molecular Formula
C13H12F2N6O
Formula Weight
306.3
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 16 mg/mlDMSO: 33 mg/mlEthanol: 20 mg/mlPBS (pH 7.2): 0.2 mg/ml
λmax
261 nm
SMILES
FC1=CC(F)=C(C(O)(CN2C=NC=N2)CN3C=NC=N3)C=C1
InChi Code
InChI=1S/C13H12F2N6O/c14-10-1-2-11(12(15)3-10)13(22,4-20-8-16-6-18-20)5-21-9-17-7-19-21/h1-3,6-9,22H,4-5H2
InChi Key
RFHAOTPXVQNOHP-UHFFFAOYSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 mg

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    Cayman Chemical
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    Product Description

    Fluconazole is a triazole antifungal agent that is effective against most Candida strains.1 In vivo fluconazole at 0.5-100 mg/kg demonstrates protective activity in various experimental animal models of systemic fungal diseases including aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, cryptococcosis, and histoplasmosis.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Herbrecht, R., Nivoix, Y., Fohrer, C., et al. Management of systemic fungal infections: Alternatives to itraconazole. J. Antimicrob. Chemother. 56(Suppl 1), i39-i48 (2005).

    2. Saag, M.S., and Dismukes, W.E. Azole antifungal agents: Emphasis on new triazoles. Antimicrob. Agents Chemother. 32(1), 1-8 (1988).