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Cannabipiperidiethanone

Item No. 11655

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-(2-methoxyphenyl)-1-[1-[(1-methyl-2-piperidinyl)methyl]-1H-indol-3-yl]-ethanone
CAS Number
1345970-43-5
Molecular Formula
C24H28N2O2
Formula Weight
376.5
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMF:PBS (pH 7.2) (1:1): 0.5 mg/mlDMSO: 5 mg/mlEthanol: 2 mg/mlMethanol: 1 mg/ml
λmax
213, 245, 303 nm
SMILES
O=C(CC1=CC=CC=C1OC)C2=CN(CC3N(C)CCCC3)C4=C2C=CC=C4
InChi Code
InChI=1S/C24H28N2O2/c1-25-14-8-7-10-19(25)16-26-17-21(20-11-4-5-12-22(20)26)23(27)15-18-9-3-6-13-24(18)28-2/h3-6,9,11-13,17,19H,7-8,10,14-16H2,1-2H3
InChi Key
AJSBNWAHEDVQJT-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Cayman Chemical
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    Product Description

    Cannabipiperidiethanone (Item No. 11655) is a synthetic cannabinoid (CB) with structural similarities to JWH 250 (Item No. 13634) and AM2233 (Item No. 11008) that has been identified as a component of "herbal" blends illegally sold in Japan.1 Cannabipiperidiethanone binds to the CB receptors CB1 and CB2 with IC50 values of 591 and 968 nM, respectively.1 Its reported affinities for CB1 and CB2 receptors are 2.3- and 9.4-fold lower than those of JWH 250, and 13- and 70-fold lower than those of (R)-(+)-WIN 55,212-2, respectively.1 This product is intended for forensic and research applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Uchiyama, N., Kikura-Hanajiri, R., and Goda, Y. Identification of a novel cannabimimetic phenylacetylindole, cannabipiperidiethanone, as a designer drug in a herbal product and its affinity for cannabinoid CB1 and CB2 receptors. Chem. Pharm. Bull. (Tokyo) 59(9), 1203-1205 (2011).

    Product Citations

    Mercier, G., Mohamed, K.A., Zagzoog, A., et al. In vitro pharmacological activity of twenty-eight synthetic cannabinoid receptor agonists at the type 1 and 2 cannabinoid receptors. Neurochem. Int. 190, 106039 (2025).