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JWH 213

Item No. 11659

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(4-ethyl-1-naphthalenyl)(2-methyl-1-pentyl-1H-indol-3-yl)-methanone
CAS Number
824959-83-3
Molecular Formula
C27H29NO
Formula Weight
383.5
Purity
≥98%
Formulation
A 10 mg/ml solution in methanol
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 5 mg/mlEthanol: 10 mg/ml
λmax
220, 319 nm
SMILES
O=C(C1=C(C=CC=C2)C2=C(CC)C=C1)C3=C(C)N(CCCCC)C4=C3C=CC=C4
InChi Code
InChI=1S/C27H29NO/c1-4-6-11-18-28-19(3)26(24-14-9-10-15-25(24)28)27(29)23-17-16-20(5-2)21-12-7-8-13-22(21)23/h7-10,12-17H,4-6,11,18H2,1-3H3
InChi Key
JAVDQKMSPNBPCK-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    JWH 213 (Item No. 11659) is a naphthoylindole-class synthetic cannabinoid (CB) which strongly binds both the central CB1 and peripheral CB2 receptor (Ki = 1.5 and 0.42 nM, respectively).1 The physiological and toxicological properties of this compound have not been evaluated. This product is intended for forensic and research applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Huffman, J.W., Zengin, G., Wu, M.J., et al. Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB1 and CB2 receptors: Steric and electronic effects of naphthoyl substituents. New highly selective CB2 receptor agonists. Bioorg. Med. Chem. 13(1), 89-112 (2005).

    Product Citations

    Mercier, G., Mohamed, K.A., Zagzoog, A., et al. In vitro pharmacological activity of twenty-eight synthetic cannabinoid receptor agonists at the type 1 and 2 cannabinoid receptors. Neurochem. Int. 190, 106039 (2025).