A prohormone of 20-hydroxy ecdysone
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α-Ecdysone

Item No. 11711

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(5β)-2β,3β,14,22R,25-pentahydroxy-cholest-7-en-6-one
CAS Number
3604-87-3
Molecular Formula
C27H44O6
Formula Weight
464.6
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 1 mg/mlDMSO: 0.1 mg/mlEthanol: 20 mg/mlEthanol:PBS (pH 7.2) (1:2): 0.1 mg/ml
λmax
242 nm
SMILES
O=C1[C@]2([H])C[C@@H](O)[C@@H](O)C[C@]2(C)[C@]3([H])C([C@@](CC[C@@H]4[C@H](C)[C@H](O)CCC(C)(O)C)(O)[C@]4(C)CC3)=C1
InChi Code
InChI=1S/C27H44O6/c1-15(20(28)8-9-24(2,3)32)16-7-11-27(33)18-12-21(29)19-13-22(30)23(31)14-25(19,4)17(18)6-10-26(16,27)5/h12,15-17,19-20,22-23,28,30-33H,6-11,13-14H2,1-5H3/t15-,16+,17-,19-,20+,22+,23-,25+,26+,27+/m0/s1
InChi Key
UPEZCKBFRMILAV-JMZLNJERSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    5 mg

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    10 mg

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    25 mg

    $687

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    Product Description

    α-Ecdysone is a prohormone of 20-hydroxy ecdysone (Item No. 16145), an insect-molting, ecdysteroid hormone.1 The insect neurohormone, prothoracicotropic hormone, stimulates prothoracic glands to release α-ecdysone, which is then rapidly converted to its active metabolite, 20-hydroxy ecdysone.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Fallon, A.M., and Gerenday, A. Ecdysone and the cell cycle: Investigations in a mosquito cell line. J. Insect Physiol. 56(10), 1396-1401 (2010).

    2. Carrow, G.M., Calabrese, R.L., and Williams, C.M. Spontaneous and evoked release of prothoracicotropin from multiple neurohemal organs of the tobacco hornworm. Proc. Natl. Acad. Sci. USA 78(9), 5866-5870 (1981).

    3. Cherbas, L., and Cherbas, P. Distribution and metabolism of α-ecdysone in pupae of the silkworm Antheraea polyphemus. Biol. Bull. 138(2), 115-128 (1970).