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(+)-ar-Turmerone

Item № 11759
CAS № 532-65-0
Purity ≥95%
product image
                (CAS 532-65-0)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     1 mg $49.00 0.00
     5 mg $221.00 0.00
     10 mg $392.00 0.00

Pricing updated 2019-04-24. Prices are subject to change without notice.

Description
Synonyms
  • (S)-(+)-ar-Turmerone

(+)-ar-Turmerone is an aromatic compound from the rhizomes of C. longa, a perennial plant of the ginger family, Zingiberaceae, commonly used in traditional Asian medicines.1 It is also a major constituent of essential oil of turmeric, which is known for its antioxidant, anti-inflammatory, and anti-nociceptive properties.2 Two structurally and physiologically distinct forms of turmerone have been isolated from C. longa, (+)-ar-Turmerone and α-turmerone.1 (+)-ar-Turmerone stimulates the proliferation of peripheral blood mononuclear cells and increases the production of TNF-α, IL-2, and IFN-γ.1 It also promotes the maturation of dendritic cells and induces the proliferation of neural stem cells both in vitro and in vivo.3,4

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Technical Information
Formal Name
2-methyl-6S-(4-methylphenyl)-2-hepten-4-one
CAS Number
532-65-0
Synonyms
  • (S)-(+)-ar-Turmerone
Molecular Formula
C15H20O
Formula Weight
216.3
Purity
≥95%
Formulation
A solution in ethanol
λmax
220, 240 nm
SMILES
CC1=CC=C([C@@H](C)CC(/C=C(C)/C)=O)C=C1
InChI Code
InChI=1S/C15H20O/c1-11(2)9-15(16)10-13(4)14-7-5-12(3)6-8-14/h5-9,13H,10H2,1-4H3/t13-/m0/s1
InChI Key
NAAJVHHFAXWBOK-ZDUSSCGKSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 1 year
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Additional Information

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References & Product Citations
Product Description References

1. Yue, G.G.L., Chan, B.C.L., Hon, P.M., et al. Evaluation of in vitro anti-proliferative and immunomodulatory activities of compounds isolated from Curcuma longa Food and Chemical Toxicology 48(8-9), 2011-2020 (2010).

2. Liju, V.B., Jeena, K., and Kuttan, R. An evaluation of antioxidant, anti-inflammatory, and antinociceptive activities of essential oil from Curcuma longa. L Indian.J.Pharmacol. 43(5), 526-531 (2011).

3. Yonggang, T., Yiming, M., Heying, Z., et al. Maturation and upregulation of functions of murine dendritic cells (DCs) under the influence of purified aromatic-turmerone (AR) Hum.Vaccin.Immunother. 8(10), 1416-1424 (2012).

4. Hucklenbrioch, J., Klein, R., Neumaier, B., et al. Aromatic-turmerone induces neural stem cell proliferation in vitro and in vivo Stem Cell Res.Ther. 5, 1-9 (2014).

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