A peptide hormone best known for its role in reproductive biology
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Oxytocin (acetate)

Item No. 11799

Technical Information
Formal Name
1,2-dithia-5,8,11,14,17-pentaazacycloeicosane, acetate
CAS Number
6233-83-6
Synonyms
  • OXT
Molecular Formula
C43H66N12O12S2 • XC2H4O2
Formula Weight
Purity
≥98%
A crystalline solid
DMF: 30 mg/mlDMSO: 14 mg/mlEthanol: 5 mg/mlPBS (pH 7.2): 5 mg/ml
λmax
278 nm
SMILES
NC(CNC([C@@H](NC([C@H]1N(C([C@@H](NC([C@H](CC(N)=O)NC([C@@H]2CCC(N)=O)=O)=O)CSSC[C@H](N)C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@]([C@@H](C)CC)([H])C(N2)=O)=O)=O)=O)CCC1)=O)CC(C)C)=O)=O.CC(O)=O
InChi Code
InChI=1S/C43H66N12O12S2.C2H4O2/c1-5-22(4)35-42(66)49-26(12-13-32(45)57)38(62)51-29(17-33(46)58)39(63)53-30(20-69-68-19-25(44)36(60)50-28(40(64)54-35)16-23-8-10-24(56)11-9-23)43(67)55-14-6-7-31(55)41(65)52-27(15-21(2)3)37(61)48-18-34(47)59;1-2(3)4/h8-11,21-22,25-31,35,56H,5-7,12-20,44H2,1-4H3,(H2,45,57)(H2,46,58)(H2,47,59)(H,48,61)(H,49,66)(H,50,60)(H,51,62)(H,52,65)(H,53,63)(H,54,64);1H3,(H,3,4)/t22-,25-,26-,27-,28-,29-,30-,31-,35-;/m0./s1
InChi Key
DSZOEVVLZMNAEH-BXUJZNQYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Oxytocin is a nonapeptide hormone primarily synthesized in magnocellular neurons of the paraventricular and supraoptic nuclei of the hypothalamus. It is known best for its role in stimulating uterine contraction and lactation and is important for social memory and attachment, sexual and maternal behavior, and aggression.1,2 Also, it has been implicated in various non-social behaviors, including learning, anxiety, feeding, and pain perception.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lee, H.J., Macbeth, A.H., Pagani, J., et alOxytocin: The great facilitator of life. Prog. Neurobiol. 88(2), 127-151 (2009).

    2. Gimpl, G., and Fahrenholz, F. The oxytocin receptor system: Structure, function, and regulation. Physiol. Rev. 81(2), 629-683 (2001).