A steroid saponin
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Product Categories

Product Type

Biochemicals
Natural Products
Saponins

Research Area

Cancer
Cell Death

Protogracillin

Item No. 11893

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3β,22α,25R)-26-(β-D-glucopyranosyloxy)-22-hydroxyfurost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-β-D-glucopyranoside
CAS Number
54848-30-5
Molecular Formula
C51H84O23
Formula Weight
1065.2
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/ml
SMILES
C[C@@]1([C@]([C@@H]2C)([H])[C@](O[C@]2(O)CC[C@@H](C)CO[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO)([H])C4)[C@]4([H])[C@@](CC=C5[C@@]6(CC[C@H](O[C@@](O[C@H](CO)[C@@H](O)[C@@H]7O[C@]([C@@H]([C@@H](O)[C@@H]8O)O)([H])O[C@@H]8CO)([H])[C@@H]7O[C@@](O[C@@H](C)[C@H](O)[C@H]9O)([H])[C@@H]9O)C5)C)([H])[C@]6([H])CC1
InChi Code
InChI=1S/C51H84O23/c1-20(19-66-45-40(62)38(60)34(56)29(16-52)69-45)8-13-51(65)21(2)32-28(74-51)15-27-25-7-6-23-14-24(9-11-49(23,4)26(25)10-12-50(27,32)5)68-48-44(73-46-41(63)37(59)33(55)22(3)67-46)43(36(58)31(18-54)71-48)72-47-42(64)39(61)35(57)30(17-53)70-47/h6,20-22,24-48,52-65H,7-19H2,1-5H3/t20-,21+,22+,24+,25-,26+,27+,28+,29-,30-,31-,32+,33+,34-,35-,36-,37-,38+,39+,40-,41-,42-,43+,44-,45-,46+,47+,48-,49+,50+,51-/m1/s1
InChi Key
GMCGZPQYTRHQRU-DKWQWWTLSA-N
Origin
Plant/Trigonella foenum
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $81

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    5 mg

    $357

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    10 mg

    $633

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    Cayman Chemical
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    Product Description

    Protogracillin is a steroid saponin originally isolated from T. terrestris.1 It is cytotoxic to K562 cells (IC50 = 3.3 µM).2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Tomova, M., Gyulemetova, R., Zarkova, S., et al. Steroidal saponins from Tribulus terrestris L. with a stimulating action on the sexual functions. 1st Int. Conf. Chem. Biotechnol. Biol. Act. Nat. Prod. 3(1), 298-302 (1982).

    2. Hu, K., Dong, A.-J., Yao, X.-S., et al. Antineoplastic steroidal saponins from rhizomes of Dioscorea collettii var. Hypoglauca. Stud. Plant Sci. 6, 220-229 (1999).