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25D-NBOMe (hydrochloride)

Item No. 11946

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • 2C-D-NBOMe
Technical Information
Formal Name
2,5-dimethoxy-N-[(2-methoxyphenyl)methyl]-4-methyl-benzeneethanamine, monohydrochloride
CAS Number
1539266-35-7
Molecular Formula
C19H25NO3 • HCl
Formula Weight
351.9
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 3 mg/mlDMSO: 5 mg/mlEthanol: 13 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
203, 220, 282 nm
SMILES
CC1=C(OC)C=C(CCNCC2=C(OC)C=CC=C2)C(OC)=C1.Cl
InChi Code
InChI=1S/C19H25NO3.ClH/c1-14-11-19(23-4)15(12-18(14)22-3)9-10-20-13-16-7-5-6-8-17(16)21-2;/h5-8,11-12,20H,9-10,13H2,1-4H3;1H
InChi Key
KJRUHRVUUSGHFU-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    2C-D (Item No. 11888), a 2,5-dimethoxy phenethylamine, is designer drug with mild hallucinogenic activity, due in part to weak activity at serotonin receptors.1,2 25D-NBOMe is a derivative of 2C-D, characterized by the addition of a benzyl-methoxy (BOMe) group to the amine. While the properties of this compound are not known, the N-(2-methoxybenzyl) addition significantly increases the affinity and activity of other disubstituted phenethylamines at the serotonin receptor 5-HT2A.3,4 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Meyer, M.R., and Maurer, H.H. Metabolism of designer drugs of abuse: An updated review. Curr. Drug Metab. 11(5), 468-482 (2010).

    2. Moya, P.R., Berg, K.A., Gutiérrez-Hernandez, M.A., et al. Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors. J. Pharmacol. Exp. Ther. 321(3), 1054-1061 (2007).

    3. Braden, M.R., Parrish, J.C., Naylor, J.C., et al. Molecular interaction of serotonin 5-HT2A receptor residues Phe3396.51 and Phe3406.52 with superpotent N-benzyl phenethylamine agonists. Mol. Pharm. 70(6), 1956-1965 (2006).

    4. Ettrup, A., Palner, M., Gillings, N., et al. Radiosysnthesis and evaluation of 11C-CIMBI-5 as a 5-HT2A receptor agonist radioligand for PET. J. Nucl. Med. 51(11), 1763-1770 (2010).