An anti-inflammatory agent
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Product Categories

Product Type

Biochemicals

Research Area

Immunology & Inflammation
Innate Immunity

MN-001

Item No. 11948

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-[6-acetyl-3-[3-[(4-acetyl-3-hydroxy-2-propylphenyl)thio]propoxy]-2-propylphenoxy]-butanoic acid
CAS Number
125961-82-2
Synonyms
  • KCA 757
  • Tipelukast
Molecular Formula
C29H38O7S
Formula Weight
530.7
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Chloroform: slightlyChloroform: Slightly soluble: 0.1-1 mg/mLEthanol: 1 mg/mlEthanol: Soluble: ≥ 10 mg/mLEthyl Acetate: SlightlyEthyl Acetate: Slightly soluble: 0.1-1 mg/mL
λmax
216, 252, 311 nm
SMILES
CC(C1=CC=C(OCCCSC(C=CC(C(C)=O)=C2O)=C2CCC)C(CCC)=C1OCCCC(O)=O)=O
InChi Code
InChI=1S/C29H38O7S/c1-5-9-23-25(14-12-22(20(4)31)29(23)36-16-7-11-27(32)33)35-17-8-18-37-26-15-13-21(19(3)30)28(34)24(26)10-6-2/h12-15,34H,5-11,16-18H2,1-4H3,(H,32,33)
InChi Key
KPWYNAGOBXLMSE-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $79

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    1 mg

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    5 mg

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    Product Description

    MN-001 is an anti-inflammatory agent.1 In vivo, MN-001 (10, 30, and 50 mg/kg) reduces the frequency of bladder voids, increases the intercontractile interval, and decreases the number of non-voiding contractions in a rat model of bladder hyperactivity induced by ovalbumin-induced mast cell stimulation.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Rajasekaran, M., Locke, K.W., and Parsons, C.L. MN-001, a novel oral anti-inflammatory agent, suppresses bladder hyperactivity in a rat model. BJU Int. 98(2), 430-434 (2006).