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THJ 018

Item No. 11962

Synonyms
Synonyms
  • JWH 018 indazole analog
Technical Information
Formal Name
1-naphthalenyl(1-pentyl-1H-indazol-3-yl)-methanone
CAS Number
1364933-55-0
Molecular Formula
C23H22N2O
Formula Weight
Purity
≥98%
Formulation
A crystalline solid
DMF: 10 mg/mlDMSO: 10 mg/mlEthanol: 10 mg/mlMethanol: 30 mg/ml
λmax
220, 320 nm
SMILES
O=C(C1=NN(CCCCC)C2=C1C=CC=C2)C3=C4C(C=CC=C4)=CC=C3
InChi Code
InChI=1S/C23H22N2O/c1-2-3-8-16-25-21-15-7-6-13-20(21)22(24-25)23(26)19-14-9-11-17-10-4-5-12-18(17)19/h4-7,9-15H,2-3,8,16H2,1H3
InChi Key
VAKGBPSFDNTMDJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    THJ 018 is an analog of JWH 018 (Item No. 10900) where the core indole structure is substituted with an indazole base. Though no biological activity has been reported for THJ 018, structurally similar analogs bind to the brain central cannabinoid (CB1) receptors and display agonist properties in functional assays, suggesting that it would have the same in vivo effects as Δ9-THC (Item No. 12068) and various synthetic CBs.1 This product is intended for forensic and research applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1.  AKB48 (APINACA) and 5F-AKB48 (5F-APINACA). (2013).

    Product Citations

    Diao, X., Wohlfarth, A., Pang, S., et alHigh-resolution mass spectrometry for characterizing the metabolism of synthetic cannabinoid THJ-018 and its 5-fluoro analog THJ-2201 after incubation in human hepatocytes. Clin. Chem. 62(1), 157-169 (2016).