A PGD1 analog
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Prostaglandin D1 Alcohol

Item No. 12002

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1,9α,15S-trihydroxy-prost-13E-en-11-one
CAS Number
1176470-37-3
Synonyms
  • PGD1 Alcohol
Molecular Formula
C20H36O4
Formula Weight
340.5
Purity
≥99%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 10 mg/mlEthanol: 15 mg/mlPBS (7.2): 75 µg/ml when added as a solut
SMILES
CCCCCC(O)/C=C/[C@H]1C(=O)CC(O)C1CCCCCCCO
InChi Code
InChI=1S/C20H36O4/c1-2-3-7-10-16(22)12-13-18-17(19(23)15-20(18)24)11-8-5-4-6-9-14-21/h12-13,16-19,21-23H,2-11,14-15H2,1H3/b13-12+/t16-,17+,18+,19-/m0/s1
InChi Key
SGFHBGFMOSYSBL-KENJKRGESA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    1 mg

    $71

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    5 mg

    $308

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    10 mg

    $547

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    Product Description

    Prostaglandin D1 (PGD1) alcohol is the synthetic analog of PGD1 with a primary alcohol in place of the C-1 carboxyl. There are no known reports of its biological activity. PGD1 is the theoretical D-series metabolite of dihomo-γ-linolenic acid (DGLA), but to date it has not been isolated as a natural product. It is an inhibitor of ADP-induced platelet aggregation in humans with an IC50 value of 320 ng/ml, about 1/10 as potent as PGD2.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bundy, G.L., Morton, D.R., Peterson, D.C., et al. Synthesis and platelet aggregation inhibiting activity of prostaglandin D analogues. J. Med. Chem. 26(6), 790-799 (1983).