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4-Methoxyamphetamine (hydrochloride)

Item No. 12041

Restricted Product (Schedule I)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • 4-MA
  • p-MA
  • para-Methoxyamphetamine
  • PMA
Technical Information
Formal Name
4-methoxy-α-methyl-benzeneethanamine, monohydrochloride
CAS Number
3706-26-1
Molecular Formula
C10H15NO • HCl
Formula Weight
201.7
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
225, 277, 283 nm
SMILES
COC1=CC=C(CC(C)N)C=C1.Cl
InChi Code
InChI=1S/C10H15NO.ClH/c1-8(11)7-9-3-5-10(12-2)6-4-9;/h3-6,8H,7,11H2,1-2H3;1H
InChi Key
VSHZXOLHFRVZND-UHFFFAOYSA-N
Regulatory Information
DEA Schedule
I
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $49

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    50 mg

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    Product Description

    4-Methoxyamphetamine (4-MA), is a serotonergic drug of the amphetamine class.1 4-MA exhibits both structural and pharmacological similarity to 3,4-methylenedioxymethamphetamine and may be a more potent hallucinogen, particularly through its effects on serotonergic transmission and through reversible inhibition of the enzyme MAO-A.1,2,3,4 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Staack, R.F., and Maurer, H.H. Metabolism of designer drugs of abuse. Curr. Drug Metab. 6(3), 259-274 (2005).

    2. Kraner, J.C., McCoy, D.J., Evans, M.A., et al. Fatalities caused by the MDMA-related drug paramethoxyamphetamine (PMA). J. Anal. Toxicol. 25(7), 645-648 (2001).

    3. Martin-Iverson, M.T., Yamada, N., By, A.W., et al. "Designer" amphetamines: Effects on behavior and monoamines with or without reserpine and/or α-methyl-para-tyrosine pretreatment. J. Psychiatr. Neurosci. 16(5), 253-261 (1991).

    4. Tseng, L.F. 5-hydroxytryptamine uptake inhibitors block para-methoxyamphetamine-induced 5-HT release. Br. J. Pharmacol. 66(2), 185-190 (1979).