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2-methoxy Ketamine (hydrochloride)

Item No. 12048

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-(2-methoxyphenyl)-2-(methylamino)-cyclohexanone, monohydrochloride
CAS Number
6728-62-7
Molecular Formula
C14H19NO2 • HCl
Formula Weight
269.8
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mlDMSO: 10 mg/mlEthanol: 10 mg/mlPBS (pH 7.2): 5 mg/ml
λmax
277 nm
SMILES
O=C1CCCCC1(C2=C(OC)C=CC=C2)NC.Cl
InChi Code
InChI=1S/C14H19NO2.ClH/c1-15-14(10-6-5-9-13(14)16)11-7-3-4-8-12(11)17-2;/h3-4,7-8,15H,5-6,9-10H2,1-2H3;1H
InChi Key
FPXCFBBCEAJUDX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    Ketamine (Item No. 11630) is a dissociative anesthetic that acts as an NMDA receptor channel blocker.1 It is regulated as a Schedule III compound in the United States. 2-methoxy Ketamine is an analog of ketamine in which the 2-chloro group is replaced with a methoxy group. The physiological and toxicological properties of this compound are unknown. This product is intended for forensic and research applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bresink, I., Danysz, W., Parsons, C.G., et al. Different binding affinities of NMDA receptor channel blockers in various brain regions-indication of NMDA receptor heterogeneity. Neuropharmacology 34(5), 533-540 (1995).

    Product Citations

    Jiang, Q., Han, J., Fine, E.J., et al. Structural basis of opioid receptor activation by PCP and ketamine. Nat. Struct. Mol. Biol. (2026).