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Item № 13184
CAS № 94105-90-5
Purity ≥98%
product image
                (CAS 94105-90-5)
     5 mg $26.00 0.00
     10 mg $49.00 0.00
     25 mg $117.00 0.00
     50 mg $208.00 0.00

Pricing updated 2019-06-15. Prices are subject to change without notice.


Equol is a nonsteroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzein by human intestinal microflora.1,2 The estrogen receptor (ER) binding activity of the naturally occurring (S)-enantiomer demonstrates greater affinity toward ERβ while the (R)-enantiomer demonstrates greater affinity towards ERα.1,2 Synthesized as a racemic mixture, (±)-equol exhibits EC50 values of 200 and 74 nM for human ERα and ERβ, respectively and induces breast cancer cell proliferation in vitro at concentrations as low as 100 nM.2,3

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Technical Information
Formal Name
CAS Number
Molecular Formula
Formula Weight
A crystalline solid
206, 225, 281 nm
InChI Code
InChI Key

Warning - this product is not for human or veterinary use.

Shipping & Storage
Room temperature in continental US; may vary elsewhere
≥ 2 years
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Additional Information

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References & Product Citations
Product Description References

1. Setchell, K.D.R., Clerici, C., Lephart, E.D., et al. S-equol, a potent ligand for estrogen receptor ß, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora American Journal of Clinical Nutrition 81, 1072-1079 (2005).

2. Muthyala, R.S., Ju, Y.H., Sheng, S., et al. Equol, a natural estrogenic metabolite from soy isoflavones: Convenient preparation and resolution of R- and S-equols and their differing binding and biological activity through estrogen receptors alpha and beta Bioorganic & Medicinal Chemistry 12, 1559-1567 (2004).

3. Liu, H., Du, J., Hu, C., et al. Delayed activation of extracellular-signal-regulated kinase ½ is involved in genistein- and equol-induced cell proliferation and estrogen-receptor-α-mediated transcription in MCF-7 breast cancer cells Journal of Nutritional Biochemistry (2009).

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