A fluorescent probe for sulfenic acid-containing proteins
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DCP-Rho1

Item No. 13194

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3,6-bis(diethylamino)-9-[2-[[4-[[3-(2,4-dioxocyclohexyl)propoxy]carbonyl]-1-piperazinyl]carbonyl]phenyl]-xanthylium, monochloride
CAS Number
1001575-98-9
Molecular Formula
C42H51N4O6 • Cl
Formula Weight
743.3
Purity
≥98%
Emission
581 nm
Excitation
560 nm
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlDMSO:PBS (pH 7.2) (1:4): 0.2 mg/mlEthanol: 5 mg/ml
λmax
258, 562 nm
SMILES
O=C(OCCCC1C(CC(CC1)=O)=O)N2CCN(C(C3=C(C4=C(C=C/5)C(OC6=CC(N(CC)CC)=CC=C64)=CC5=[N+](CC)\CC)C=CC=C3)=O)CC2.[Cl-]
InChi Code
InChI=1S/C42H51N4O6.ClH/c1-5-43(6-2)30-16-19-35-38(26-30)52-39-27-31(44(7-3)8-4)17-20-36(39)40(35)33-13-9-10-14-34(33)41(49)45-21-23-46(24-22-45)42(50)51-25-11-12-29-15-18-32(47)28-37(29)48;/h9-10,13-14,16-17,19-20,26-27,29H,5-8,11-12,15,18,21-25,28H
InChi Key
WQLZVTHQGGHUNF-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    500 µg

    $107

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    1 mg

    $203

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    Product Description

    DCP-Rho1 is a fluorescent probe for the detection of sulfenic acid-containing proteins.1,2 It displays excitation/emission maxima of 560/581 nm, respectively, and has been used to visualize protein oxidation sites in situ.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Klomsiri, C., Rogers, L.C., Soito, L., et al. Endosomal H2O2 production leads to localized cysteine sulfenic acid formation on proteins during lysophosphatidic acid-mediated cell signaling. Free Rad. Biol. Med. 71, 49-60 (2014).

    2. Holmila, R.J., Vance, S.A., Chen, X., et al. Mitochondria-targeted probes for imaging protein sulfenylation. Sci. Rep. 8(1), 6635 (2018).