Biotinylation reagent
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Biotin-NHS

Item No. 13315

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
6aR-hexahydro-2-oxo-2,5-dioxo-1-pyrrolidinyl ester-1H-thieno[3aS,4-d]imidazole-4S-pentanoic acid
CAS Number
35013-72-0
Synonyms
  • Biotin N-hydroxysuccinimide ester
  • NSC 345668
Molecular Formula
C14H19N3O5S
Formula Weight
341.4
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlDMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
SMILES
O=C1N[C@H]2CS[C@@H](CCCCC(=O)ON3C(=O)CCC3=O)[C@H]2N1
InChi Code
InChI=1S/C14H19N3O5S/c18-10-5-6-11(19)17(10)22-12(20)4-2-1-3-9-13-8(7-23-9)15-14(21)16-13/h8-9,13H,1-7H2,(H2,15,16,21)/t8-,9-,13-/m0/s1
InChi Key
YMXHPSHLTSZXKH-RVBZMBCESA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    100 mg

    $79

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    250 mg

    $183

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    500 mg

    $345

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    1 g

    $610

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    Product Description

    N-Hydroxysuccinimide (NHS) activates carboxylic acid groups (on biotin) to facilitate coupling reactions. Biotin-NHS is a compound used to attach biotin to primary amines under alkaline conditions (pH~8-9). For example, lysines on the surface of proteins, including antibodies, are ideal targets for biotinylation with this compound.

    WARNING This product is not for human or veterinary use.