A potent PPARα agonist
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Product Type

Small Molecule Modulators
Receptor Pharmacology
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Application

AM3102

Item No. 13452

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[(1R)-2-hydroxy-1-methylethyl-9Z-octadecenamide
CAS Number
213182-22-0
Synonyms
  • KDS-5104
Molecular Formula
C21H41NO2
Formula Weight
339.6
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 20 mg/mlEthanol: 5 mg/ml
SMILES
OC[C@@H](C)NC(CCCCCCC/C=C\CCCCCCCC)=O
InChi Code
InChI=1S/C21H41NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-21(24)22-20(2)19-23/h10-11,20,23H,3-9,12-19H2,1-2H3,(H,22,24)/b11-10-/t20-/m1/s1
InChi Key
IPVYNYWIRWMRHH-JPMGXVIASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 mg

    $49

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    10 mg

    $93

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    50 mg

    $376

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    100 mg

    $655

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    Product Description

    AM3102 is an OEA analog that stimulates PPARα transcriptional activity with an EC50 value of 100 nM and prolongs feeding latency in rodents with an ED50 value of 2.4 mg/kg.1 It is resistant to enzymatic hydrolysis and is as potent as OEA in enhancing transcriptional activity of PPARα and reducing food intake in free-feeding rats.1,2 AM3102 demonstrates weak affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors with Ki values of 33 and 26 µM, respectively.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Astarita, G., Di Giacomo, B., Gaetani, S., et al. Pharmacological characterization of hydrolysis-resistant analogs of oleoylethanolamide with potent anorexiant properties. J. Pharmacol. Exp. Ther. 318(2), 563-570 (2006).

    2. Wang, J., and Ueda, N. Role of the endocannabinoid system in metabolic control. Curr. Opin. Nephrol. Hypertens. 17(1), 1-10 (2008).

    3. Lin, S., Khanolkar, A.D., Fan, P., et al. Novel analogues of arachidonylethanolamide (anandamide): Affinities for the CB1 and CB2 cannabinoid receptors and metabolic stability. J. Med. Chem. 41(27), 5353-5361 (1998).