For immunochemical analysis of SIRT7
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SIRT7 Polyclonal Antibody

Item No. 13477

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • Silent Information Regulator 7
  • SIR2
  • Sirtuin 7
Immunogen
human SIRT7 amino acids 35-51 and 361-377
Formulation (Request formulation change)
100 µg of protein G-purified IgG in 200 µl PBS containing 0.2% gelatin and 0.05% sodium azide
Host
Rabbit
Applications
WB
Species Reactivity
(+) Human SIRT7
Origin
Animal/Rabbit
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    1 ea

    $356

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    Product Description

    SIRT7 is a member of a famiy of proteins called sirtuins (SIR2-like proteins) and are present in prokaryotes and eukaryotes. All SIR2-like proteins have a sirtuin core domain, which contains a series of sequence motifs conserved in organisms ranging from bacteria to humans. Bacterial, yeast, and mammalian sirtuins are able to metabolize NAD+ and several act as mono-ADP-ribosyltransferases. The enzymatic function of sirtuins is not yet completely understood but recent reports of histone-activated SIR2-mediated NAD+ metabolism and NAD+-activated SIR2-mediated histone deacetylation suggest a possible coupled reciprocal activation mechanism involving interactions of SIR2 with NAD+ and the N-ε-acetyl-lysine groups of acetylated histone.

    WARNING This product is not for human or veterinary use.