For immunochemical analysis of HDAC7
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HDAC7 (Phospho-Ser155) Polyclonal Antibody

Item No. 13500

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • Histone Deacetylase 7
Immunogen
synthetic peptide from human HDAC7 containing phospho-ser155
Formulation (Request formulation change)
50 µg of peptide-purified IgG in 100 µl of PBS containing 0.05% BSA and 0.05% sodium azide
Host
Rabbit
Applications
WB
Species Reactivity
(+) Human HDAC7(+) Canine HDAC7(+) Chimpanzee HDAC7(+) Cow HDAC7(+) Monkey HDAC7(+) Mouse HDAC7(+) Rat HDAC7
Origin
Animal/Rabbit
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    1 ea

    $399

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    Product Description

    Histone deacetylase 7 (HDAC7) is a thymus-specific, intracellular transcription factor belonging to the class IIa HDAC family. Reports suggest that dephosphorylation and nuclear localization of HDAC7 is promoted by myosin phosphatase, thus regulating the repression of Nur77 and inhibition of apoptosis in CD4+/CD8+ double-positive thymocytes. HDAC7 plays a specific role in maintaining vascular integrity by repressing the expression of matrix metalloproteinase (MMP) 10. It promotes repression mediated by transcriptional corepressor NCOR2 and is an efficient corepressor of the androgen receptor (AR). It is also responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3, and H4).

    WARNING This product is not for human or veterinary use.