An inactive diastereomer of MG132
Related Products
Diastereomer(s)
10012628MG132
Isomer(s)
45205γ–Secretase Inhibitor I
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(R)-MG132

Item No. 13697

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
benzyl ((S)-4-methyl-1-(((R)-4-methyl-1-(((S)-4-methyl-1-oxopentan-2-yl)amino)-1-oxopentan-2-yl)amino)-1-oxopentan-2-yl)carbamate
CAS Number
1211877-36-9
Synonyms
  • ​Cbz-L-Leu-D-Leu-L-Leucinal
Molecular Formula
C26H41N3O5
Formula Weight
475.6
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 25 mg/ml
SMILES
O=C(OCC1=CC=CC=C1)N[C@@H](CC(C)C)C(N[C@H](CC(C)C)C(N[C@H](C=O)CC(C)C)=O)=O
InChi Code
InChI=1S/C26H41N3O5/c1-17(2)12-21(15-30)27-24(31)22(13-18(3)4)28-25(32)23(14-19(5)6)29-26(33)34-16-20-10-8-7-9-11-20/h7-11,15,17-19,21-23H,12-14,16H2,1-6H3,(H,27,31)(H,28,32)(H,29,33)/t21-,22+,23-/m0/s1
InChi Key
TZYWCYJVHRLUCT-ZRBLBEILSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    5 mg

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    10 mg

    $423

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    25 mg

    $924

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    Cayman Chemical
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    Product Description

    (R)-MG132 is an inactive diastereomer of the proteasome inhibitor MG132 (Item No. 10012628). Based on internal testing, (R)-MG132 does not inhibit the 20S proteasome and can, therefore, be used as a negative control for MG132 activity.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Citations

    Change, Y.-C., Chen, Y.-J., Huang, C.-W., et al. Cyclic stretch facilitates myogenesis in C2C12 myoblasts and rescues thiazolidinedione-inhibited myotube formation. Front. Bioeng. Biotechnol. 4(27), (2016).