For immunochemical analysis of Histone H3.3
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Histone H3.3 Polyclonal Antibody

Item No. 13784

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Synonyms
  • H3.3A
  • H3F3A
  • H3.3B
  • H3F3B
Immunogen
synthetic peptide from human Histone H3.3 amino acids 100-136
Formulation (Request formulation change)
100 µg protein A-purified IgG in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide
Host
Rabbit
Applications
IHC and WB
Species Reactivity
(+) Human Histone H3.3(+) Chicken Histone H3.3(+) Drosophila Histone H3.3(+) Equine Histone H3.3(+) Mouse Histone H3.3(+) Opossum Histone H3.3(+) Ovine Histone H3.3
Origin
Animal/Rabbit
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

    1 ea

    $363

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    Product Description

    Histone H3.3 is a nuclear protein and a replication-independent member of the histone H3 family that has a role in nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. H3.3 constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. It has a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. Expression of H3F3A is common throughout the cell cycle independent of DNA synthesis.

    WARNING This product is not for human or veterinary use.