A prodrug form of ganciclovir
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Valganciclovir (hydrochloride)

Item No. 13875

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester L-valine, monohydrochloride
CAS Number
175865-59-5
Synonyms
  • Ro 107-9070/194
Molecular Formula
C14H22N6O5 • HCl
Formula Weight
390.8
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 1 mg/mlDMSO: 20 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
255 nm
SMILES
CC(C)[C@H](N)C(OCC(CO)OCN1C(NC(N)=NC2=O)=C2N=C1)=O.Cl
InChi Code
InChI=1S/C14H22N6O5.ClH/c1-7(2)9(15)13(23)24-4-8(3-21)25-6-20-5-17-10-11(20)18-14(16)19-12(10)22;/h5,7-9,21H,3-4,6,15H2,1-2H3,(H3,16,18,19,22);1H/t8?,9-;/m0./s1
InChi Key
ZORWARFPXPVJLW-MTFPJWTKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 mg

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    Cayman Chemical
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    Product Description

    Valganciclovir is a valyl ester prodrug form of the antiviral nucleoside analog ganciclovir (Item No. 13853). In vivo, valganciclovir (200 mg/kg) increases survival and reduces weight loss in an immunosuppressed hamster model of disseminated adenovirus type 5 (Ad5) infection.1 Formulations containing valganciclovir have been used in the prevention of post-transplant cytomegalovirus (CMV) infections.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Toth, K., Ying, B., Tollefson, A.E., et al. Valganciclovir inhibits human adenovirus replication and pathology in permissive immunosuppressed female and male Syrian hamsters. Viruses 7(3), 1409-1428 (2015).